1865
In the Krakow Scientific Society (TNK), the Physiographic Commission (KF) is created with the Zoological Section (initiator: Maximilian Siła-Nowicki). The evidence collections are collected at the Jagiellonian University Zoological Office at St. Anne's Street.
1868
The edition of the Yearbook Report of the Physiographic Commission begins.
1870
KF receives the highest storey of the “Wężyków” building at Sławkowska Street for the Museum room.
1873
TNK is converted into the Academy of Skills, which takes over the KF together with the Museum. The curator of the KF Museum is Stanisław Zastarzy, geologist and entomologist.
1891
The main library of the AU separated the natural library, which becomes the beginning of the KF Library.
1910-1914
Extension of the AU building with new rooms of the Physiographic Museum on the highest storey.
1919-1920
As a result of the competition written after the death of W. Kulczyński by the Polish Academy of Skills (PAU), the directorate of the Phyosoology Museum includes Jan Stach - entomologist and paleoteriologist.
1929-1930
Excavations in the natural wax mine in Staruni; extraction of ‘The Second Old Rhino’
1945
KF solution; the facility adopts the name of the PAU Natural Museum and is still headed by J. Stach.
1952 – 1953
After the creation of the Polish Academy of Sciences (and the suspension of PAU activities), the zoological part of the Natural Museum (including the paleontology of Pleistocene) is incorporated into the Zoological Institute of the Polish Academy of Sciences in Warsaw as its Kraków branch. The other two sections of the Museum were incorporated into other units of the PAN; the scientific collections and the library were divided into three parts. In 1953 the edition of "Folia Biologica" began
1956
Launch of the “Acta Zoologica Cracoviensia” edition under the editorial board of Jan Stach.
1962
The exclusion of the Kraków branch from the Zoological Institute in Warsaw as a standalone facility under the name of the Department of Systematic Zoology (ZZS) PAS under the direction of Kaziemierz Kowalski.
1969
Fusion with the Polish Academy of Sciences, the Department of Experimental Zoology of the Polish Academy of Sciences and the Cracow Laboratory of Neuroanatomy of the Nencki Institute; the Department of Systematic and Experimental Zoology of the Polish Academy of Sciences is established
1989
The decision of Prime Minister Mazowiecki raised the rank of the facility by giving it the current name of the Institute of Systematics and Evolution of Animals of the Polish Academy of Sciences (ISEZ PAN).
1992
Purchase and adaptation of the building of B. Łaź Romanska at St. Sebastian for exhibition, warehouses and workshops of the ISEZ PAS Nature Museum.